List of posters

Topics: Cardio-vascular computing, Mathematical biomedical models

Keywords: 0D-1D coupling, Multiphysics modelling, Cardiovascular modelling, Wave propagation

Understanding the complex interactions between the heart and the arterial and venous networks in physiological and pathological scenarios remains a significant challenge in cardiovascular research. Computational cardiovascular models show promise as an effective tool for exploring these complexities, but to tackle such interactions methodological challenges must be addressed.

We present a cardiovascular closed-loop model that couples a 1D global vascular model [1] with a 0D cardiac model (namely, the CircAdapt model [2]). This coupling enables detailed analysis of the interaction between the heart and the circulatory system, with emphasis on venous return, while maintaining a low computational cost. In particular, the use of a 1D model of blood flow enables to efficiently analyse wave propagation phenomena. Suitable coupling conditions are considered to ensure the integration of the two models while preserving their coherence and consistency.

The model's output is validated against physiological data from literature. Finally, selected cardiovascular pathologies will be simulated to investigate how changes in vascular properties affect the cardiac function.